How do we get CBDa to CBD? Decarboxylation explained

How do we get CBDa to CBD? Decarboxylation explained


CBD is extracted from hemp, but did you know it is actually found naturally in its acidic form? So naturally in raw hemp you will find it contains mostly cannabidiolic acid (CBDa) and actually very little CBD at all.

So how do we convert cannabidiolic acid to cannabidiol?

To do this, we use a process called decarboxylation.

This means the loss of a carbonyl group from the molecule resulting in the loss of carbon dioxide. This is performed through using heat to catalyse the reaction.

Shown in the reaction below, the area highlighted in yellow is what makes the molecule acidic, and is a carbonyl group. Through the application of heat this functional group is lost, resulting in an end product of cannabidiol and the evolution of CO2 gas.



CBDa to CBD decarboxylation

CBDa to CBD and the loss of Carbon dioxide



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